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Why the Same Dose Stops Triggering Dopamine When you use nicotine repeatedly , your nicotinic receptors become desensitized , they fundamentally shut down temporarily despite nicotine being present, which blunts the dopamine surge you once felt
The reported population-level trends in smoking, the countrys longest-running epidemic, might be a result of distinct, time-varying factors like age (association between age and smoking status), and/or period (differences in smoking prevalence due to changing sociocultural environments that shape smoking practices collectively among all individuals), and/or cohort (shifts in smoking status among groups of individuals that belong to different generations) 1,5,6
A total of 56 participants attended one of 15 FGDs (Table 1)
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